Rajahmundary (Andhra Pradesh) has a large and diverse population of sex workers operating in varying environments. CARE, through the SAKSHAM programme, undertakes a Community Led Structural Intervention (CLSI) which addresses the various issues that these vulnerable women are confounded with. It recognises that vulnerability to transmission and infection of HIV/AIDS is embedded in social, economic and political structures that control people’s lives. SAKSHAM works in partnership with the community to address structural issues that will reduce vulnerability to HIV.